Huang M, Turpin JA, Graham L, Janini GM, Covell DG, Maynard A and Rice WG. 1997. Anti-HIV agents that selectively target retroviral nucleocapsid protein zinc fingers without affecting cellular zinc finger proteins. 5th Conference on Retroviruses and Opportunistic Infections.
Turpin JA, Schaeffer CA, Terpening SJ, Graham L, Bu M, Sausville EA and Rice WG. 1996. Reverse transcription of human immunodeficiency virus type 1 is blocked by retroviral zinc finger inhibitors. Antiviral Chemistry and Chemotherapy. 8:60-69.
Rice WG, Baker D, Field L, Schaeffer CA, Graham L, Bu M, Terpening S, Clanton D, Schultz R, Bader JP, Buckheit, RW, Jr. and Turpin JA. 1996. Inhibition of multiple phases of HIV-1 replication by a dithiane compound that attacks the conserved zinc fingers of retroviral nucleocapsid proteins. Antiviral Agents and Chemotherapy. 41:419-426.
Rice WG, Turpin JA, Schaeffer CA, Graham L, Clanton D, Buckheit RW, Zaharevitz D, Summers MF, Wallqvist A and Covell DG. 1996. Evaluation of selected chemotypes in coupled cellular and molecular target-based screens identifies novel HIV-1 zinc finger inhibitors. J. Med. Chem. 39:3606-3616.
Wang S, Milne GWA, Yan X, Posey I, Nicklaus MC, Graham L and Rice WG. 1996. Discovery of novel, non-peptide HIV-1 protease inhibitors by pharmacophore searching. J. Med. Chem. 39:2047-2054.
Rice WG, Supko JG, Malspeis L, Clanton DJ, Bu M, Graham L, Schaeffer CA, Turpin JA, Domagala J, Gogliotti R, Bader JP, Halliday SM, Coren L, Arthur LO, Henderson LE and Buckheit RW, Jr. 1995. Novel inhibitors of HIV-1 p7NC zinc fingers as candidates for the treatment of AIDS. Science. 270:1194-1197.
Cushman M, Golebiewski WM, Pommier Y, De Clercq E, Graham L and Rice WG. 1995. Cosalane analogues with enhanced potencies as inhibitors of HIV-1 protease and integrase. J. Med. Chem. 38:443-452.
Rice WG, Schaeffer CA, Bu M, Graham L, Buckheit RW, Jr., Clanton D and Turpin JA. 1995. HIV-1 replication is unaffected by human secretory leukocyte protease inhibitor. Antiviral Research. 29:269-277.
Turpin JA, Schaeffer CA, Graham L, Bu M, Buckheit RW, Jr., Felsted R and Rice WG. 1995. Blockage of HIV-1 release from latently infected cells by disulfide-substituted benzamide compounds that attack retroviral zinc fingers. Antimicrobial Agents and Chemotherapy. 42:487-494.
Cushman M, Golebiewski M, Buckheit RW, Jr., Graham L and Rice WG. 1995. Synthesis of certain alkenyldiarylmethanes (ADAM's) and novel anti-HIV-1 agents which act as non-nucleoside reverse transcriptase inhibitors. Bio. Med. Chem. Lett. 5:2713-2716.
Cushman M, Golebiewski M, Buckheit RW, Jr., Graham L and Rice WG. 1995. Synthesis and biological evaluation of an alkenyldiarylmethane (ADAM) which acts as a novel non-nucleoside HIV-1 reverse transcriptase inhibitor. J. Med. Chem. 39:3217-3227.
Cushman M, Golebiewski WM, McMahon JB, Buckheit RW, Jr., Clanton DJ, Weislow O, Haugwitz RD, Bader JP, Graham L and Rice WG. 1994. Design, synthesis, and biological evaluation of cosalane, a novel anti-HIV agent which inhibits multiple features of virus reproduction. J. Med. Chem. 37:3040-3050.
Rice WG, Schaeffer CA, Graham L, Bu M, McDougal JS, Orloff SL, Villinger F, Young M, Oroszlan S, Fesen M, Pommier Y, Mendeleyev J and Kun E. 1993. The site of antiviral action of 3-nitrosobenzamide on the infectivity process of human immunodeficiency virus in human lymphocytes. Proc. Natl. Acad. Sci. USA 90:9721-9724.
Meier HL, Papirmeister B, Gross CL, Kilduff J and Graham LM. 1985. Regulation of histamine release from human leukocytes by the serine esterase: I. The direct release of histamine by the serine esterase inhibitors diisopropylfluorophosphate (DFP) and Soman (GD) J. Immunol. Open Literature Publication.
Turpin JA, Schaeffer C, Terpening S, Graham L, Bu M, Buckheit RW, Jr., Felsted RL and Rice WG. 1996. Disulfide substituted benzamides crosslinking virion and cell-associated retroviral zinc finger containing proteins. Keystone Symposia, Immunopathogenesis of HIV Infection.
Rice WG, Buckheit RW, Jr., Clanton D, Domagala J, Gogliotti R, Bu M, Graham L, Schaeffer CA, Turpin JA, Bader, JP, Halliday SM, Arthur LO and Henderson LE. 1995. Novel disulfide-substituted benzamide (DIBA) inhibitors of HIV-1 p7NC protein zinc fingers as candidates for the treatment of AIDS. 35th Interscience Conference on Antimicrobial Agents and Chemotherapy.
Bu M, Turpin JA, Schaeffer CA, Graham L, Buckheit RW, Jr., and Rice WG. 1995. Secretory leukocyte protease inhibitor (SLPI) does not effectively inhibit HIV-1 replication. 35th Interscience Conference on Antimicrobial Agents and Chemotherapy.
Schaeffer CA, Turpin JA, Rice WG, Bu M, Graham L, Arthur LO, Henderson LE, Mendeleyev J and Kun E. 1995. 4-iodo-3-nitrobenzamide (I-NO2BA) as a prodrug that targets HIV-1 p7 nucleocapsid protein zinc fingers as a potential treatment for HIV infection. 35th Interscience Conference on Antimicrobial Agents and Chemotherapy.
Cushman M, Golebiewski WM, Pommier Y, Mazumder A, Reymen D, De Clercq E, Weislow O, Buckheit RW, Jr., McMahon JB, Clanton DJ, Graham L and Rice WG. 1995. New anti-HIV agents which inhibit multiple stages of the viral replication cycle. 1995 Canadian Society of Chemistry Conference.
Meier HL, Lusco CT, Gross CL, Graham LM, Krebs RC and Johnson JB. 1987. Human lymphocytes as a model for sulfur mustard toxicicity. Soc. of Toxicol.
Johnson JB, Lusco CT, Gross CL, Graham LM and Meier HL. 1987. Inhibitors of poly (ADP-ribose) polymerase prevent cellular toxicity by the alkylating agent, 2,2' dichlorodiethyl sulfide (sulfur mustard, HD).
Graham LM, Gross CL, Maxwell DM, Papirmeister B and Meier HL. 1986. The dual role of serine esterases in regulation of histamine release (HR) from human basophils. Fed. Fros. 45:1352.
Graham LM, Gross CL, Papirmeister B, Kagey-Sobotka A and Meier HL. 1985. Inhibition of serine esterase-dependent histamine release (HR) from human basophils by atropine. Fed. Proc. 44:5343.
Meier HL, Gross, CL, Johnson JB, Graham LM and Lusco CT. 1987. The development of an in vitro model to determine the efficacy of prophylactic and therapeutic compounds for mustard injury. RSG-3 Meeting, Brussels, Belgium.